Document 2325
 DOCN  M94A2325
 TI    Partner change and the risk of HIV-1 infection in two Ugandan
       populations.
 DT    9412
 AU    Malamba S; Kamali A; Kengeya-Kayondo JF; Okongo M; Nunn AJ; Mulder DW;
       Medical Research Council (UK) Programme on AIDS in Uganda,; Entebbe.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):33 (abstract no. 106C). Unique
       Identifier : AIDSLINE ICA10/94370250
 AB    OBJECTIVES: To compare HIV-1 infection rates by reported number of
       lifetime sexual partners in a rural cohort and an urban trading centre.
       METHODS: A population cohort of 15 neighbouring rural villages in Masaka
       District, SW Uganda has been kept under ethnodemographic, medical and
       serological surveillance since 1989. HIV-1 serology and information on
       numbers of lifetime sexual partners were obtained from 2704 adults (aged
       13+ years) in the rural cohort. The same information was obtained from
       389 adults in a cross-sectional study done in a near-by urban centre.
       HIV-1 sero status was determined using 2 independent ELISA. RESULTS:
       HIV-1 adult seroprevalence rates were 8% in the rural and 40% in the
       urban population. Because of the weak association between HIV-1
       infection rates and the number of reported lifetime sexual partner in
       those aged 35 or more, the analysis has been restricted to those aged
       13-34 years. Rates of infection in the urban centre were high for all
       numbers of lifetime sexual partners and increased steeply in those
       reporting 0 to 3 partners with no further increase thereafter. In
       contrast, rates of infection in the rural cohort increased with
       increasing number of partners to 10 or more (p < 0.001 for trend).
       CONCLUSION: The results of this study show a strong association between
       HIV-1 infection rates, the number of reported lifetime sexual partners
       and back-ground HIV-1 prevalence rates. These results indicate that it
       is possible to obtain meaningful data on sex history through population
       surveys. TABULAR DATA, SEE ABSTRACT VOLUME.
 DE    Acquired Immunodeficiency Syndrome/PSYCHOLOGY/*TRANSMISSION  Adolescence
       Adult  Cohort Studies  Cross-Sectional Studies  Female  Human  HIV
       Seroprevalence  *HIV-1  Male  Population Surveillance  Rural Population
       *Sex Behavior  Sexual Partners  Uganda/EPIDEMIOLOGY  Urban Population
       MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).